AMINOGLYCOSIDES

in blurtindia •  last year 

This ars the medicinal and Bacteriocidal category of traditional gram negative antibacterial medication that inhibit the protein synthesis and contain as a portion of molecules and amino sugars ..
There are many aminoglycosides like streptomycin, Gentamicin, kanamycin, neomycin....
They act by penetrate into bacterial cell wall yo reach pero plasmic through poring channel it is passive diffusion and further transport cross the cytoplasmic membrane than it enters into the 30s ribosomal sub unit than it inhibit protein synthesis by inducing misreading of genetic code on the mRNA break up of polysomes into monomer
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It is effective against TB in combination with other antibiotics for active TB it is given together with isoniazid, pyrazinamide

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